GLP-1 Titration Schedule Calculator
View official step-up escalation schedules, maintenance targets, and cumulative dosage timelines for semaglutide, tirzepatide, and retatrutide.
GLP-1 Dose Escalation Principles
Written out so you can check it by hand. The app runs this exact function — not a second implementation that drifts.
GLP-1 and multi-agonist peptide protocols follow structured multi-week escalation ramps to balance efficacy with gastrointestinal tolerability.
1. Initiation Step: Week 1–4 starting doses (e.g. 0.25 mg Semaglutide or 2.5 mg Tirzepatide) are non-therapeutic starting steps designed to establish receiver tolerance.
2. 4-Week Escalation Window: Doses step up every 4 weeks to match steady-state receptor equilibration.
3. Maintenance Phase: Reached once the target clinical dose is achieved, where dosing remains steady.
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